I say, Watson,’ he whispered, ‘would you be afraid to sleep in the same room as a lunatic, a man with softening of the brain, an idiot whose mind has lost its grip?’ ‘Not in the least,’ I answered in astonishment. ‘Ah, that’s lucky,’ he said, and not another word would he utter that night.
I consider that a man's brain originally is like a little empty attic, and you have to stock it with such furniture as you choose. [...] It is a mistake to think that that little room has elastic walls and can distend to any extent. [...] It is of the highest importance, therefore, not to have useless facts elbowing out the useful ones.
I cannot live without brainwork. What else is there to live for? Stand at the window here. Was ever such a dreary, dismal, unprofitable world? See how the yellow fog swirls down the street and drifts across the duncoloured houses. What could be more hopelessly prosaic and material?
There was a brisk northern wind, heavy and wet with the salt of the sea, and he felt, as he turned his face to it, fresh life and strength surging in his blood and bracing his limbs.
I am engaged in answering that Italian buffoon, Mazotti, whose views upon the larval development of the tropical termites have excited my derision and contempt . . .
By a man's finger-nails, by his coat-sleeve, by his boots, by his trouser-knees, by the callosities of his forefinger and thumb, by his expression, by his shirt-cuff — By each of these things a man's calling is plainly revealed. That all united should fail to enlighten the competent inquirer in any case is almost inconceivable. You know that a conjurer gets no credit when once he has explained his trick; and if I show you too much of my method of working, you will come to the conclusion that I am a very ordinary individual after all.
...Holmes, who loathed every form of society with his whole Bohemian soul, remained in our lodgings in Baker Street, buried among his old books, and alternating from week to week between cocaine and ambition, the drowsiness of the drug, and the fierce energy of his own keen nature.