Remember the Three Princes of Serendip who went out looking for treasure? They didn't find what they were looking for, but they kept finding things just as valuable. That's serendipity, and our business [drugs] is full of it.
But by far the greatest obstacle to the progress of science and to the undertaking of new tasks and provinces therein is found in this-that men despair and think things impossible.
Science was false by being unpoetical. It assumed to explain a reptile or a mollusk, and isolated it-which is hunting for life in graveyards. Reptile or mollusk or man or angel only exists in system, in relation.
It cannot be that axioms established by argumentation should avail for the discovery of new works, since the subtlety of nature is greater many times over than the subtlety of argument. But axioms duly and orderly formed from particulars easily discover the way to new particulars, and thus render sciences active.
When even the brightest mind in our world has been trained up from childhood in a superstition of any kind, it will never be possible for that mind, in its maturity, to examine sincerely, dispassionately, and conscientiously any evidence or any circumstance which shall seem to cast a doubt upon the validity of that superstition. I doubt if I could do it myself.
The sceptic will say, 'It may well be true that this system of equations is reasonable from a logical standpoint, but this does not prove that it corresponds to nature.' You are right, dear sceptic. Experience alone can decide on truth.
LEAD, n. A heavy blue-gray metal much used ... as a counterpoise to an argument of such weight that it turns the scale of debate the wrong way. An interesting fact in the chemistry of international controversy is that at the point of contact of two patriotisms lead is precipitated in great quantities.
[Newton wrote to Halley ... that he would not give Hooke any credit] That, alas, is vanity. You find it in so many scientists. You know, it has always hurt me to think that Galileo did not acknowledge the work of Kepler.