Remember the Three Princes of Serendip who went out looking for treasure? They didn't find what they were looking for, but they kept finding things just as valuable. That's serendipity, and our business [drugs] is full of it.
Pure mathematics is, in its way, the poetry of logical ideas. ... [By seeking] logical beauty spiritual formulas are discovered necessary for the deeper penetration into the laws of nature.
"She can't do Subtraction." said the White Queen. "Can you do Division? Divide a loaf by a knife-what's the answer to that?" "I suppose-" Alice was beginning, but the Red Queen answered for her. "Bread-and-butter, of course."
What opposite discoveries we have seen! (Signs of true genius, and of empty pockets.) One makes new noses, one a guillotine, One breaks your bones, one sets them in their sockets; But vaccination certainly has been A kind antithesis to Congreve's rockets.
Science is a wonderful thing if one does not have to earn one's living at it. One should earn one's living by work of which one is sure one is capable. Only when we do not have to be accountable to anybody can we find joy in scientific endeavor.
We must not overlook the role that extremists play. They are the gadflies that keep society from being too complacent or self-satisfied; they are, if sound, the spearhead of progress. If they are fundamentally wrong, free discussion will in time put an end to them.
The intellect has little to do on the road to discovery. There comes a leap in consciousness, call it Intuition or what you will, the solution comes to you and you don't know how or why.
In my opinion there is no other salvation for civilization and even for the human race than the creation of a world government with security on the basis of law. As long as there are sovereign states with their separate armaments and armament secrets, new world wars cannot be avoided.
Next you'd see a raft sliding by, away off yonder, and maybe a galoot on it chopping. . . you'd see the ax flash and come down-you don't hear nothing; you see the ax go up again, and by the time it's above the man's head then you hear the k'chunk!-it had took all that time to come over the water.
The astronomers said, 'Give us matter and a little motion and we will construct the universe. It is not enough that we should have matter, we must also have a single impulse, one shove to launch the mass and generate the harmony of the centrifugal and centripetal forces.' ... There is no end to the consequences of the act. That famous aboriginal push propagates itself through all the balls of the system, and through every atom of every ball.
Every improvement that is put upon the real estate is the result of an idea in somebody's head. The skyscraper is another idea; the railroad is another; the telephone and all those things are merely symbols which represent ideas. An andiron, a wash-tub, is the result of an idea that did not exist before.
[Newton wrote to Halley ... that he would not give Hooke any credit] That, alas, is vanity. You find it in so many scientists. You know, it has always hurt me to think that Galileo did not acknowledge the work of Kepler.