Remember the Three Princes of Serendip who went out looking for treasure? They didn't find what they were looking for, but they kept finding things just as valuable. That's serendipity, and our business [drugs] is full of it.
We have lost the art of living, and in the most important science of all, the science of daily life, the science of behavior, we are complete ignoramuses. We have psychology instead.
What a deep faith in the rationality of the structure of the world and what a longing to understand even a small glimpse of the reason revealed in the world there must have been in Kepler and Newton to enable them to unravel the mechanism of the heavens in long years of lonely work!
Evolution is the law of policies: Darwin said it, Socrates endorsed it, Cuvier proved it and established it for all time in his paper on The Survival of the Fittest. These are illustrious names, this is a mighty doctrine: nothing can ever remove it from its firm base, nothing dissolve it, but evolution.
More than the diamond Koh-i-noor, which glitters among their crown jewels, they prize the dull pebble which is wiser than a man, whose poles turn themselves to the poles of the world, and whose axis is parallel to the axis of the world. Now, their toys are steam and galvanism.
The End of our Foundation is the knowledge of Causes; and secret motions of things; and the enlarging of the bounds of Human Empire, to the effecting of all things possible.
Doctor Johnson said, that in sickness there were three things that were material; the physician, the disease, and the patient: and if any two of these joined, then they get the victory; for, Ne Hercules quidem contra duos [Not even Hercules himself is a match for two]. If the physician and the patient join, then down goes the disease; for then the patient recovers: if the physician and the disease join, that is a strong disease; and the physician mistaking the cure, then down goes the patient: if the patient and the disease join, then down goes the physician; for he is discredited.
For myself, I like a universe that, includes much that is unknown and, at the same time, much that is knowable. A universe in which everything is known would be static and dull, as boring as the heaven of some weak-minded theologians. A universe that is unknowable is no fit place for a thinking being. The ideal universe for us is one very much like the universe we inhabit. And I would guess that this is not really much of a coincidence.