The infinitude of creation is great enough to make a world, or a Milky Way of worlds, look in comparison with it what a flower or an insect does in comparison with the Earth.
The discovery of truth is prevented more effectively, not by the false appearance things present and which mislead into error, not directly by weakness of the reasoning powers, but by preconceived opinion, by prejudice.
If someone separated the art of counting and measuring and weighing from all the other arts, what was left of each (of the others) would be, so to speak, insignificant.
You can get into a habit of thought in which you enjoy making fun of all those other people who don't see things as clearly as you do. We have to guard carefully against it.
The End of our Foundation is the knowledge of Causes; and secret motions of things; and the enlarging of the bounds of Human Empire, to the effecting of all things possible.
The secrets of evolution are death and time-the deaths of enormous numbers of lifeforms that were imperfectly adapted to the environment; and time for a long succession of small mutations.
And one of the three great things in the world is gossip, you know. First there's religion; and then there's science; and there's-and then there's friendly gossip. Those are the three-the three great things.
Take an arrow, and hold it in flame for the space of ten pulses, and when it cometh forth you shall find those parts of the arrow which were on the outsides of the flame more burned, blacked, and turned almost to coal, whereas the midst of the flame will be as if the fire had scarce touched it. This is an instance of great consequence for the discovery of the nature of flame; and sheweth manifestly, that flame burneth more violently towards the sides than in the midst.
Remember the Three Princes of Serendip who went out looking for treasure? They didn't find what they were looking for, but they kept finding things just as valuable. That's serendipity, and our business [drugs] is full of it.
Scientists constantly get clobbered with the idea that we spent 27 billion dollars on the Apollo programs, and are asked "What more do you want?" We didn't spend it; it was done for political reasons. ... Apollo was a response to the Bay of Pigs fiasco and to the successful orbital flight of Yuri Gagarin. President Kennedy's objective was not to find out the origin of the moon by the end of the decade; rather it was to put a man on the moon and bring him back, and we did that.
The scientist finds his reward in what Henri Poincare calls the joy of comprehension, and not in the possibility of application to which any discovery may lead.
I like the scientific spirit-the holding off, the being sure but not too sure, the willingness to surrender ideas when the evidence is against them: this is ultimately fine-it always keeps the way beyond open.
Widespread intellectual and moral docility may be convenient for leaders in the short term, but it is suicidal for nations in the long term. One of the criteria for national leadership should therefore be a talent for understanding, encouraging, and making constructive use of vigorous criticism.
Religions are tough. Either they make no contentions which are subject to disproof or they quickly redesign doctrine after disproof. ... near the core of the religious experience is something remarkably resistant to rational inquiry.
Astronomy is a cold, desert science, with all its pompous figures,-depends a little too much on the glass-grinder, too little on the mind. 'T is of no use to show us more planets and systems. We know already what matter is, and more or less of it does not signify.